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FDA-Approved vs Compounded Distinction: FDA-approved semaglutide (Wegovy) is a finished product that has undergone full FDA review for safety, effectiveness, and quality for weight management indications

A placebo-controlled trial of subcutaneous semaglutide in nonalcoholic steatohepatitis, The New England Journal of Medicine (2021) Nonalcoholic steatohepatitis (NASH), Cedars-Sinai Treatment of Alzheimers disease: Beyond symptomatic therapies, International Journal of Molecular Sciences (2023) Semaglutide treatment of excessive body weight in obese PCOS patients unresponsive to lifestyle programs, Journal of Clinical Medicine (2023) The impact of insulin resistance on loss of lung function and response to treatment in asthma, American Journal of Respiratory and Critical Care Medicine (2022) The relationship between the use of GLP-1 receptor agonists and the incidence of respiratory illness: a meta-analysis of randomized controlled trials, Diabetology & Metabolic Syndrome (2023) Highlights of prescribing information, Food and Drug Administration (2023) Drug label information, DailyMed (2023) Medications containing semaglutide marketed for Type 2 diabetes or weight loss, Food and Drug Administration (2024) Diabetic nephropathy (kidney disease), Johns Hopkins Medicine Safety of semaglutide, Frontiers in Endocrinology (2021) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

A prospective open-label pilot study of fluvastatin on proinflammatory and prothrombotic biomarkers in antiphospholipid antibody positive patients

Link NEJM

Key takeaways Drinking alcohol while on Zepbound may increase the risk of side effects, including nausea, indigestion, and blood sugar changes